LIVER CIRRHOSIS
FREQUENCY AND SEVERITY OF HYPONATREMIA IN PATIENTS
DOI:
https://doi.org/10.29309/TPMJ/2015.22.04.1318Keywords:
Cirrhosis, hyponatremia, liver, sodium, and chronic liver disease - CLDAbstract
Liver cirrhosis results from prolonged, widespread but patchy hepato-cellular
necrosis due to various reasons. Objectives: To determine the frequency and severity of
hyponatremia in patients with liver cirrhosis. Study Design: Descriptive case series study.
Period: Six months. Setting: Liaquat University Hospital Hyderabad. Methods: The cirrhotic
subjects were assessed for hyponatremia and its severity. The data was analyzed in SPSS 16
and the frequency and percentage was calculated for hyponatremia and statistically p -value
≤0.05 was considered as significant. Result: Sixty five percent males and thirty five percent
females of liver cirrhosis were studied. The mean age ± SD of overall cirrhotic subjects was
40.79±7.83. The hyponatremia was identified in 72% (51 males and 21 females) patients. The
mean ±SD for Na+ level in overall population was 129.73±83.51 while it was 119.92±3.61 in
hyponatraemic cirrhotic subjects. The sodium level in male and female hyponatraemic cirrhotic
patients was 121.73±8.63 and 118.92±3.31. Conclusions: Dilutional hyponatremia is frequent
in patients with liver cirrhosis.
