ST ELEVATION MYOCARDIAL INFARCTION

HYPONATREMIA AND ITS PROGNOSTIC IMPORTANCE

Abstract

OBJECTIVE: To evaluate the frequency of hyponatremia and its prognostic
importance in ST elevation myocardial infarction. Period: Six months. Design: Case series.
Setting: Tertiary care hospital Hyderabad. Methods: All the cases with ST elevation myocardial
infarction admitted in the CCU were recruited and evaluate for serum sodium level at admission
and then at 24, 48 and 72 hours. The data was analyzed in SPSS 16 and the frequency and
percentage was calculated. Results: One hundred patients with acute myocardial infarction
were recruited and assessed for sodium level. The mean age ±SD of whole population was
57.52±9.51 whereas in male and female population it was 58.72±7.53 and 53.84±7.93
respectively. The sodium level was 130.21±3.42 and 127.41±4.21 in male and female
population. The p-value was statistically significant (<0.01) in context to age and sex whereas
the age in context to hyponatremia is non significant (p=0.77). The hyponatremia and its
severity was statistically significant in context to sex (p=0.04) and duration of the myocardial
infarction (p=0.03). The serum sodium level in context to duration of MI was also significant
(p=0.03) whereas the mortality at the end of 30 days was 11% of which 02 patients had normal
sodium level while the 09 had low sodium level (hyponatremia). Conclusion: Hyponatremia in
patients with acute STEMI is a important predictor of thirty days mortality.