HELICOBACTER PYLORI INFECTION
C-REACTIVE PROTEIN IN PATIENTS
DOI:
https://doi.org/10.29309/TPMJ/2013.20.05.1210Keywords:
C-reactive protein,, CRP,, Helicobacter pylro,, H. pylori,, Dyslipidemia,, Lipid profile.Abstract
Objective: To determine the frequency of raised C-reactive protein in patients with Helicobacter pylori infection. Design:
Cross sectional descriptive study. Setting: Department of Medicine at Liaquat University Hospital (tertiary care teaching hospitals).
Period: April 2012 to September 2012. Patients and methods: All patients above 12 years of age, of either gender with history of nausea,
vomiting, recurrent abdominal pain, dyspepsia or abdominal discomfort, heartburn, bloating and halitosis through casualty outdoor
department (COD) or admitted in medical unit were evaluated and enrolled in the study. For the detection of Helicobacter pylori the 3 cc
venous blood sample of relevant patients was taken in a disposable syringe. After detecting the H. pylori infection, the H. pylori individuals
were further evaluated for serum C-reactive protein by taking 3cc venous blood sample in a disposable syringe and sent to laboratory for
analysis. The patients with raised CRP were also evaluated for their lipid profile to detect dyslipidemia. The data was collected on
predesigned proforma and then entered, saved and analyzed in SPSS version 10.00. Results: During six month study period total 92
patients with Helicobacter pylori infection were recruited and studied for serum C-reactive protein. The mean age ± SD for overall
population was 43.22±8.31, whereas the mean age ±SD for male and female population was 41.24±7.94 and 44.76±9.42
respectively. The raised CRP was detected in 61(66%) patients (p=0.02). The mean value ± SD of raised CRP in male and female
population was 6.30±2.86 and 7.82±3.21 respectively. Of 61(66%) patients with raised CRP the dyslipidemia was identified in 45(74%)
patients (p=0.03). Out of 45, the raised triglycerides was observed in 08(18%) patients, low HDL in 10(22%) patients, raised LDL in
13(29%), raised cholesterol in 07(16%) whereas 07(16%) patients had mix dyslipidemia. Conclusions: The raised CRP was identified in
patients with Helicobacter pylori infection, the dyslipidemia was observed in raised CRP population.
