Frequency of early stent thrombosis in patients presenting with STEMI Undergoing Primary Percutaneous Coronary Intervention (PPCI) at a Tertiary Care Hospital.

Abstract

Objective: To determine the frequency of early stent thrombosis in patients presenting with STEMI undergoing PPCI. Study Design: Case Series. Setting: Department of Cardiology at Sheikh Zayed Hospital, Rahim Yar Khan. Period: October 2025 to March 2026. Methods: The patients were selected using non-probability consecutive sampling and a total of 234 patients with an age range of 18-60 years and STEMI who underwent PPCI were included in the study. Demographic, clinical, biochemical, angiographic, and procedural characteristics were recorded. Patients were followed for 30 days after PPCI for the development of early stent thrombosis. SPSS version 23 was used for data analysis. Results: The mean age of the patients was 54.9 ± 9.2 years, and 78.6% were male patients. Common comorbidities were dyslipidemia (70.1%), hypertension (47.9%), and diabetes mellitus (44.9%). There were 13 (5.6%) patients with early stent thrombosis. The commonest presenting symptom was chest pain. The involvement of the culprit vessel was statistically significant (p=0.028) in association with early stent thrombosis, and there were no other significant associations with the demographic and clinical variables. Conclusion: Early stent thrombosis is still a clinically relevant complication following PPCI in STEMI patients. Strategies to minimize thrombotic complications and enhance patient outcomes may include careful procedural planning, aggressive management of risk factors, and monitoring to ensure proper post-procedural care.