PRETERM LABOUR

FREQUENCY OF HYPOMAGNESAEMIA IN PRETERM LABOUR

Abstract

Objectives: To determine the frequency of hypomagnesaemia in women with
preterm labour. Study Design: Cross sectional study. Settings: Department of obstetrics &
gynaecology Nishtar Hospital Multan. Duration of Study: From 10th November 2016 to 10th May
2017. Subject and Methods: A total of 219 pregnant women with singleton pregnancy, preterm
labour and parity 1 – 4 were included in the study. Women with history of diabetes, hypertension
smoking and polyhhydramnious amniotic fluid index (AFI)>25 cm on ultrasound were excluded.
Venous blood was drawn from entire subjects to evaluate the serum magnesium level and sent
immediately to laboratory for analysis venous blood samples were obtained by venepuncture
and collected in lithium heparin specimen bottles. Data was collected for hypomagnesaemia.
Results: Age range in this study was from 20 to 40 years with mean age of 30.356±3.60 years,
mean parity 1.936± 0.96, mean gravida 2.936 ± 0.96, mean gestational age 32.000±2.25
weeks and mean BMI was 27.337 ± 1.67 kg/m2. Majority of the patients were from 20 – 30 years
(51.1%). History of preterm delivery was 17.4%. Majority of patients belong to middle economic
status (66.2%). Hypomagnesaemia was seen in 37.9% patients. Conclusion: it is concluded
that low serum magnesium (hypomagnesaemia) is associated with preterm onset of labour.
Maternal hypomagnesaemia may be used as a predictor of preterm labour.