SMOKELESS TOBACCO;

SERUM FERRITIN AND VITAMIN B12 IN RELATION TO C REACTIVE PROTEIN IN INDIVIDUALS. HYDERABAD SINDH BASED STUDY.

Authors

  • Imran Ali Shaikh Liaquat University of Medical and Health Sciences Jamshoro Sindh, Pakistan.
  • Naila Masood Liaquat University of Medical and Health Sciences Jamshoro Sind, Pakistan.
  • Fouzia Aijaz Sheikh LUMHS Jamshoro.
  • Talha Shaikh Liaquat University of Medical and Health Sciences Jamshoro Sind, Pakistan.

DOI:

https://doi.org/10.29309/TPMJ/2017.24.09.881

Keywords:

Manpuri,, Betel Nut,, Gutka,, Hyderabad,, Sindh.

Abstract

Objectives: To know the serum ferritin and vitamin B12 levels in relation to C
reactive protein in individuals using smokeless tobacco in Hyderabad, sindh, Pakistan. Study
Design: Cross sectional study. Place of Study: Private clinics of consultants of Hyderabad,
Sindh, Pakistan. Duration of Study: January 2016 to February 2017. Methodology: One
hundred eighty three individuals were selected from different clinics of physicians, dental
surgeons of sadder Hyderabad sindh Pakistan by judgmental sampling. Patients were young
subjects, mean age was 21.4±7.4 years, mean BMI was 22.1±3.8 and mean duration of
chewing tobacco was 2±1.5 years. All types and forms of gutaka, manpuri and flavored betel
nut were included like bombart, zafri and panparag. The dose was 30-100grams once or two
times. SPSS 16 was used as statical software and Chai square test was used to calculate
p value. P value was taken <0.05 statically significant. Results: Frequency of use of gutka
was 32%, Betel nut 38% and 29% had habit of chewing manpuri. Serum ferritin was low and
c reactive protein was high, p value was <0.05 in gutaka and manpuri users. Vitamin B12
was reduced significantly in gutaka user p value was <0.05. In betel nut chewers significant
finding was only high C reactive protein, p value <0.04. Conclusion: Smokeless tobacco has
significant negative impact on serum ferritin and vitamin B12 levels. These chewing agents also
increased inflammatory markers like c reactive protein.

Author Biographies

Imran Ali Shaikh, Liaquat University of Medical and Health Sciences Jamshoro Sindh, Pakistan.

FCPS
Professor of Medicine

Naila Masood, Liaquat University of Medical and Health Sciences Jamshoro Sind, Pakistan.

MD
Associate Professor of Medicine

Fouzia Aijaz Sheikh, LUMHS Jamshoro.

DCH
Senior Lecturer, 

Talha Shaikh, Liaquat University of Medical and Health Sciences Jamshoro Sind, Pakistan.

House officer department of
Dentistry

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Published

2017-09-08