ESSENTIAL HYPERTENSION

HYPERURICEMIA IN PATIENTS

Abstract

Objectives: To determine the frequency of hyperuricemia in patients with
essential hypertension. Study Design: Cross sectional descriptive. Period: Six months study.
Setting: Liaquat University Hospital Hyderabad. Patients and Methods: All the patients with
essential hypertension visited at cardiac OPD / admitted in the ward were further evaluated for
serum uric acid level. The data was analyzed in SPSS 16 and the frequency and percentage was
calculated. Results: During six months study period, total one hundred and eighty (180) patients
with essential hypertension were recruited and study for uric acid level. The mean age ±SD
for overall population was 52.84±8.72 whereas it was 55.83±7.93 and 50.75±8.95 in male and
female population respectively. The mean ± SD of systolic and diastolic blood pressure (mmHg)
in overall population was 160.50 ± 12.74 and 100.70±5.95 respectively. The mean ±SD serum
uric acid level in overall population was 13.74±4.83 while it was 11.74±6.44 and 14.43±4.31 in
male and female population respectively). The male population was predominant in relation to
age (p=0.02), the hyperuricemia was identified in 117/180 (65%) patients and it is statistically
significant in context to age (p<0.01) and gender (p<0.05) whereas mean ±SD of systolic and
diastolic blood pressure was also significant in relation to hyperuricemia. Conclusion: There is
a relationship between hyperuricemia and hypertension and shown that the serum uric acid level
was significantly increased in patients with essential hypertension.