METABOLIC SYNDROME;

ARE OUR WOMEN AT RISK TO DEVELOP. A STUDY AT ABBASI SHAHEED HOSPITAL

Abstract

Metabolic syndrome is a congregation of central obesity, dyslipidemia, raised blood
sugar levels, increasing the individual’s susceptibility to Type II Diabetes and cardiovascular
diseases. Objectives: (1) To determine the prevalence of metabolic syndrome in young, urban,
female population. (2) To determine the risk factors in poor, urban, female population. Study
Design: This was a descriptive cross sectional study. Setting: The department of Gynae/
Obst Unit II KMDC/Abbasi Shaheed hospital. Period: One year starting from January 2016 to
December 2016. Material and Method: Approval was taken from ESRC of KMDC. All healthy
asymptomatic married/single women between 18-49 years of age were included while women
<18 or >50 years of age, diabetic, hypertensive or having bleeding disorders were excluded
from study. Laboratory data included blood sugar, triglycerides, HDL-cholesterol, collected by
phlebotomist from the participants in fasting state through venipuncture. A Chi-square test was
applied to evaluate the association of demographic group variables and metabolic syndrome.
P-value <0.05 was considered as statistically significant. There was no conflict of interest. Result:
A total of 343 participants were recruited. The socio and demographic data is summarized in
Table-I. The prevalence of Metabolic syndrome was found to be high. 227(66.2%) of participants
were having Metabolic syndrome according to NCEP ATP III criteria. 63(18.4 %) had history of
PIH while 52(15.2%) had family history of hypertension and 126(36.7 %) had family history
of both Hypertension and Diabetes. 232 (67.6 %) of women had sedentary life style and only
3(0.9%) practiced aerobic exercises. 287(83.7%) had their waist circumference of >80cm, the
mean systolic blood pressure was 127.5 +-23.76 while the mean diastolic blood pressure was
86.99+-57.36. The mean of BMI was at higher level 30.97+-6.41. Obesity is the most common
risk factor for Metabolic syndrome. The mean of fasting blood sugar was 105.08+-42.16
which was on higher side. The mean of Triglycerides 142.43+-61.12 and HDL 39.04+-12.45
were within normal limits. Increased prevalence was observed in women who had PIH during
pregnancy and childbirth 25.1% v 5.2%(p value=0.001). Conclusion: Prevention and treatment
of metabolic syndrome is a big challenge. Lifestyle interventions should begin from the early
childhood to reduce weight and to prevent development of obesity and metabolic syndrome.