Efficacy of topical steroid in treatment of hyper granulation tissue in burn patients: A randomized control trial.
Keywords:Burn, Bactigrass, Debridement, Hyper Granulation, Split Thickness Graft, Topical Steroid
Objective: To determine the efficacy of topical steroid in treatment of hyper granulation tissue in burn patients in term of healing time. Study Design: Randomized Control Trial (RCT). Setting: Jinnah Burn & Reconstructive Surgery Center, Allama Iqbal Medical College, Lahore. Period: May 2017 to November 2017. Material & Methods: A total of 32 patients fulfilling the inclusion criteria were enrolled in the study. Patients were randomly divided into 2 groups with 16 patients in each group by lottery method. Written informed consent was obtained from all patients. In group A, topical 1% hydrocortisone (Fusidin H) cream was applied and Group B received Medicated Paraffin gauze (bactigrass) dressing. Wound assessment was done weekly by 2 consultant plastic surgeons and final assessment was done at 3weeks after the treatment. Results: The mean age of patients was 28.6 + 8.81 years, among them 22(68.8%) were male and 10(31.3%) were females. Mean healing time in Group A and Group B was 12.8 +2.08 days and 15.4+1.6 days respectively. Efficacy was calculated as P value of 0.12 which is significant (p < 0.05). Conclusion: Topical steroid (hydrocortisone 1%) is more effective in treatment of hyper granulation in post burn wounds with early healing than medicated paraffin gauze dressing.
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