Potential pharmacological and non-pharmacological interventions for coronavirus disease 2019 (COVID-19): A Narrative Review.

  • Taha Bin Arif Dow Medical College, Dow University of Health Sciences, Karachi.
  • Javeria Saquib Dow University of Health Sciences, Karachi
  • Ayman Iqbal Dow Medical College, Dow University of Health Sciences, Karachi.
  • Shajeea Arshad Ali Dow Medical College, Dow University of Health Sciences, Karachi.
  • Farea Ahmed Dow Medical College, Dow University of Health Sciences, Karachi.
Keywords: Antiviral Therapy, Coronavirus Disease 2019, Convalescent Plasma, Hand Hygiene, Mesenchymal Stem Cell Therapy, Preventive Measures, Personal Protective Equipment, Severe Acute Respiratory Syndrome Coronavirus 2, Social Distancing, Vaccine

Abstract

Coronavirus disease 2019 (COVID-19) originated in Wuhan, China, and subsequently spread to 215 countries and territories. Due to the high transmission rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the disease has been declared as a pandemic by the World Health Organization (WHO). Scientists are striving to investigate and contribute new findings of the disease to the literature, especially related to the treatments and preventive measures that can be undertaken to curb its transmission. Multiple studies regarding medical interventions such as antivirals use, mesenchymal stem cell therapy, and convalescent plasma therapy have been published to date. Furthermore, non-pharmacological measures including the usage of personal protective equipment, undertaking proper hand hygiene, and social distancing has been reported to suppress the spread of this infection. However, a definite cure has not been discovered yet. In this review, we have summarized the effectiveness, potential risks, and side effects of all pharmacological agents and non-pharmacological preventive strategies as well as the prospects of possible vaccine for COVID-19.

Author Biographies

Taha Bin Arif, Dow Medical College, Dow University of Health Sciences, Karachi.

MBBS Final Year Student

Javeria Saquib, Dow University of Health Sciences, Karachi

MBBS Fourth Year Student

Dow Medical College,

Ayman Iqbal, Dow Medical College, Dow University of Health Sciences, Karachi.

MBBS Fourth Year Student

Shajeea Arshad Ali, Dow Medical College, Dow University of Health Sciences, Karachi.

MBBS Final Year Student

Farea Ahmed, Dow Medical College, Dow University of Health Sciences, Karachi.

MBBS Fourth Year Student

Published
2021-04-10