Pre and postnatal assessment of gross parameters after utilization of high fat diet in rats.

  • Shahid Maqbool Korai Al-Tibri Medical College and Hospital, Karachi.
  • Hina Khan Al-Tibri Medical College and Hospital, Karachi.
  • Shahid Hussain Soomro Chandka Medical College Shaheed Benazir Butto Medical University Larkana.
  • Muhammad Rafique Al-Tibri Medical College and Hospital, Isra University Karachi.
  • Raja Faisal Al-Tibri Medical College and Hospital Karachi.
  • Mazhar-ul- Haque Shahida Islam Medical College Lodhra.
Keywords: High Fat Diet, Maternal, Pre and Postnatal, Weight

Abstract

Objective: To assess the gross parameters of maternal weight and abdominal circumference upon utilization of high fat diet. Study Design: Experimental study. Setting: Al-Tibri Medical College and Hospital. Period: October 2019 to March 2020. Material & Methods: After taken an ethical approval total 16 female albino rats were selected and divided into two groups through randomized sampling and 2 male rats were introduced in each group for the purpose of mating, group A given a normal diet (control) and group B given a composition of high fat diet throughout the gestational period. The weights of the pregnant rats and the abdominal circumference were measured on day 1st and 21st of gestation. The data were analyzed through SPSS version 21.0, in the form of Mean ± standard deviation, and for the evaluation of level of significance independent “t” test was applied and considered value of significant was P=<0.05. Results: There was no significant difference in the weight or abdominal circumference of maternal rats in both groups. Conclusion: High fat diet having no significant effects on maternal weight and abdominal circumference as compared to normal diet. We need to assess other histomorphological parameters to assess the relative effects.

Author Biographies

Shahid Maqbool Korai, Al-Tibri Medical College and Hospital, Karachi.

MBBS, M.Phill,

Senior Lecturer Anatomy

Hina Khan, Al-Tibri Medical College and Hospital, Karachi.

MBBS, M.Phill, CCRP, Cmed

Associate Professor of Anatomy

Deputy Director Research and PG Affairs,

Shahid Hussain Soomro, Chandka Medical College Shaheed Benazir Butto Medical University Larkana.

MS Surgery

Associate Professor Anatomy

Muhammad Rafique, Al-Tibri Medical College and Hospital, Isra University Karachi.

MBBS, M.Phill

Professor Anatomy & Principal

Raja Faisal, Al-Tibri Medical College and Hospital Karachi.

MBBS, M.Phill

Assistant Professor Anatomy

Mazhar-ul- Haque, Shahida Islam Medical College Lodhra.

MBBS, M.Phill

Associate Professor

Published
2021-04-10