Pre and postnatal assessment of gross parameters after utilization of high fat diet in rats.
Objective: To assess the gross parameters of maternal weight and abdominal circumference upon utilization of high fat diet. Study Design: Experimental study. Setting: Al-Tibri Medical College and Hospital. Period: October 2019 to March 2020. Material & Methods: After taken an ethical approval total 16 female albino rats were selected and divided into two groups through randomized sampling and 2 male rats were introduced in each group for the purpose of mating, group A given a normal diet (control) and group B given a composition of high fat diet throughout the gestational period. The weights of the pregnant rats and the abdominal circumference were measured on day 1st and 21st of gestation. The data were analyzed through SPSS version 21.0, in the form of Mean ± standard deviation, and for the evaluation of level of significance independent “t” test was applied and considered value of significant was P=<0.05. Results: There was no significant difference in the weight or abdominal circumference of maternal rats in both groups. Conclusion: High fat diet having no significant effects on maternal weight and abdominal circumference as compared to normal diet. We need to assess other histomorphological parameters to assess the relative effects.