MALIGNANT THYROID DISEASE;

HYPOCALCAEMIA FOLLOWING THYROID SURGERY

Authors

  • Altaf Ahmed Talpur LUMHS, Jamshoro.
  • Bheesham Kumar NMC Specialty Hospital Abu Dhabi, UAE.
  • Ahsan Ali Laghari LUMHS, Jamshoro.
  • Abdul Qadeer Shikh Icahn School of Medicine Mount Sinai, Newyork, USA.
  • Afzal Junejo LUMHS Jamshoro.
  • Ali Akber Ghumro Peoples Medical College, Nawabshah.

DOI:

https://doi.org/10.29309/TPMJ/2017.24.12.560

Keywords:

Thyroid Malignancy/Surgery/Hypocalcemia.

Abstract

Objectives: To determine frequency of Transient & permanent hypocalcemia
after Thyroid Surgery for Malignant thyroid disease. Study Design: Observational study.
Setting: Public & Private Sector Hospitals of Hyderabad. Period: December 2008 to April 2016.
Materials and Methods: All patients of Thyroid pathology who fulfilled the inclusion criteria
were admitted in the ward. They were evaluated preoperatively & surgery was performed.
Postoperatively patients were assessed clinically & biochemically for Hypocalcaemia. Patient’s
data was recorded & analyzed for variables like age, sex, diagnosis of thyroid disease on FNAC,
Type of thyroid Malignancy, type of thyroid surgery, Transient & permanent hypocalcemia in
relation to type of type of thyroid surgery performed & the hospital stay. Results: Total 254
patients were operated for different thyroid pathologies. It includes 91(35.82%) male & and
163 (64.17%) female patients making ratio of 1: 1.79. Mean age was 37.29 ±7.4 years.
Amongst them 33 patients were diagnosed as Malignant Thyroid diseases. Most common
type of thyroid malignancy detected was papillary carcinoma in 48.48% patients followed by
follicular carcinoma in 42.42% patients. Most common surgical procedures performed includes
completion thyroidectomy in 57.57% patients with 01(3.03%) of them underwent cervical
neck dissection followed by total thyroidectomy in 36.36% patients with 02(6.06%) of them
underwent cervical neck dissection. Postoperative hypocalcemia was noted in 45.45% patients
with 36.36% patients developed hypocalcemia within 24 hours of operation, 6.06% within 24
to 48 hours & 3.03% patients after 48 hours of surgery. Transient hypocalcemia was noticed in
13/33 (39.39%) cases & permanent hypocalcemia in 02/33(6.06%) patients. Mean hospital stay
was 4.13± 0.32 days. Conclusion: Hypocalcaemia was noted in 15(45.45%) patients operated
for thyroid Malignancy. Revision surgery & cervical lymph node dissection were noted as risk
factors.

Author Biographies

Altaf Ahmed Talpur, LUMHS, Jamshoro.

FCPS
Associate Professor
Surgery unit – IV

Bheesham Kumar, NMC Specialty Hospital Abu Dhabi, UAE.

MBBS,
Senior Medical Officer

Ahsan Ali Laghari, LUMHS, Jamshoro.

FCPS, MS
Assistant Professor Surgery

Abdul Qadeer Shikh, Icahn School of Medicine Mount Sinai, Newyork, USA.

MBBS,
MPH student

Afzal Junejo, LUMHS Jamshoro.

Incharge Surgical Unit – IV

Ali Akber Ghumro, Peoples Medical College, Nawabshah.

FCPS (General Surgery)
Ex-Professor of Surgery

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Published

2017-11-29