SURGICAL SITE INFECTION

PROPHYLACTIC ANTIBIOTICS IN LAPAROSCOPIC CHOLECYSTECTOMY TO REDUCE SURGICAL SITE INFECTION

  • Syed Muhammad Nauman CMH Quetta.
  • Yousaf Haroon CMH Nowshera.
  • Asrar Ahmad CMH Nowshera.
  • Irum Saleem
Keywords: Laparoscopic Cholecystectomy, Antibiotic Prophylaxis, Surgical Site Infection

Abstract

Objectives: To compare antibiotic prophylaxis in preventing frequency of
postoperative surgical site wound infection rate in low risk laparoscopic cholecystectomy
with controls. Study design: Randomized Controlled Trial. Setting: Department of Surgery,
Combined Military Hospital, Rawalpindi. Duration of study: This study was conducted from
11-07-2015 to 10-01-2016. Subjects and methods: A total of 650 patients (325 in each group)
were included in the study. Patients in group-A received antibiotic prophylaxis whereas patients
in group-B did not receive any antibiotic prophylaxis. Results: Mean age of the patients was
44.91±13.37 and 42.28±13.76 years in group-A and B, respectively. In group-A there were
152 patients (46.7%) and in group-B 148 patients (45.5%) were males. In group-A 173 patients
(53.3%) and in group-B 177 patients (54.5%) were females. In group-A, superficial site infection
was seen in 4 patients (1.2%) and in group-B superficial site infection was observed in 13
patients (4.0%). The difference between two groups was statistically significant (p=0.027).
Mean duration of symptoms was 5.75±0.50 and 5.77±0.92 days in group-A and B, respectively.
Stratification with regard to age, gender and duration of symptoms was carried out. Conclusion:
In conclusion, we recommend the use of pre-operative prophylactic antibiotics for patients
who are undergoing elective low-risk laparoscopic cholecystectomy inorder to prevent postoperative
infectious complications.

Author Biographies

Syed Muhammad Nauman, CMH Quetta.

MBBS
Registrar Surgery

Yousaf Haroon, CMH Nowshera.

MBBS, FCPS
Consultant Surgeon

Asrar Ahmad, CMH Nowshera.

MBBS, FCPS (Surgery),
FCPS (Paediatric Surgery)
Consultant General and Paediatric Surgeon

Irum Saleem

MBBS
Medical Officer

Published
2018-01-10