Comparison of recovery time of ketamine versus nalbuphine used in combination with propofol in females undergoing in-vitro fertilization under intravenous sedation.

  • Muazzam Butt Ameer ud Din Medical College / LGH Lahore.
  • Saadia Khalique Services Institute of Medical Sciences, Services Hospital Lahore.
  • Hamza Waheed Kaul Associates, Lahore.
  • Shumaila Athar Kaul Associates, Lahore.
  • Zulqarnain Butt Avicenna Medical College, Lahore.
  • Mohsin Riaz Askri Allied Hospital, Faisalabad.
Keywords: Ketamine, Nalbuphine, Propofol, IVF

Abstract

Objective: To compare the mean recovery time after administration of propofol-ketamine versus propofol-nalbuphine combination in patients undergoing in-vitro fertilization procedures under intravenous sedation. Study Design: Randomized control trial. Setting: Department of Anesthesiology, Hameed Latif Hospital, Lahore. Period: 14/11/2016 to 14/11/2017. Material & Methods: 60 Married females of age between 20 to 35 years undergoing elective in-vitro fertilization surgeries of ASA I and II with weight 50-70 kg were included. Group A was treated with nalbuphine and propofol while group B with ketamine and propofol and mean recovery time was calculated. Results: In this study there were total 60 cases, 30 in each group included. The mean age in group A was 27.53±3.36 years while in group B was 26.33±2.44 years. The mean weight in group A was 63.45±3.21 years while in B was 62.78±5.23 years. Recovery time was significantly better in group A (nalbuphine) where it was seen as 4.73±0.98 minutes as compared to 7.17±1.14 minutes in group B with p= 0.01. Recovery time was better in younger age groups (20-27) and again was significantly better in nalbuphine group revealing it in 4.43±0.91 minutes with p= 0.01. Conclusion: The recovery time of nalbuphine is significantly better than ketamine group when combined with propofol.

Author Biographies

Muazzam Butt, Ameer ud Din Medical College / LGH Lahore.

MBBS, FCPS

Assistant Professor Anesthesia

Saadia Khalique, Services Institute of Medical Sciences, Services Hospital Lahore.

MBBS, FCPS

Associate Professor Anesthesia

Hamza Waheed, Kaul Associates, Lahore.

MBBS, FCPS

Consultant Anesthetist

 

Shumaila Athar, Kaul Associates, Lahore.

MBBS, FCPS

Senior Consultant Anesthetist

 

Zulqarnain Butt, Avicenna Medical College, Lahore.

MBBS, FCPS

Assistant Professor Anesthesia

 

Mohsin Riaz Askri, Allied Hospital, Faisalabad.

MBBS, FCPS

Assistant Professor Anesthesia

Faisalabad Medical University/

 

Published
2021-02-10