POST PARTUM IRON DEFICIENCY ANEMIA;
COMPARATIVE EFFICACY AND SAFETY OF INTRAVENOUS VS ORAL IRON THERAPY
DOI:
https://doi.org/10.29309/TPMJ/2017.24.01.475Keywords:
Post-partum iron deficiency anemia,, oral iron,, parenteral iron,, hemoglobin.Abstract
Objectives: To Analyze and compare the effect of oral vs parenteral iron therapy
on various hematological parameters in women suffering from post-partum iron deficiency
anemia. Study Design: Comparative, randomized and prospective study. Setting: Department
of Pharmacology, HCMD, HU in collaboration with the Dept of Obs/Gynae, JPMC Karachi.
Period: January to December 2015. Subjects and Methods: 40 patients divided in two groups
A and B of 20 each. Group A received oral iron (Tab Iberet 525 mg once daily) for a period of 3
months while group B was treated with intravenous iron sucrose complex (Inj Venofer 100mg/
Amp) the total no of doses were calculated according to Hemoglobin deficit. Hemoglobin,
Hematocrit and MCV were observed at day 0, 45 and 90 of the treatment. Results: Group A
shows a mean increase of 25.85% at day 90th of the treatment in comparison to this group B
shows a much better result with a mean increase of 36.71% in Hemoglobin conc. At the end of
12 weeks therapy. Conclusion: Parenteral iron therapy was found to be an effective means of
treatment in patients with postpartum iron deficiency anemia.
