Hypertonic saline versus normal saline nebulization in hospitalized children with acute bronchiolitis.

Authors

  • Maleeha Saleem The Children’s Hospital & ICH, Multan.
  • Maria Saleem The Children’s Hospital & ICH, Multan.
  • Asim Khurshid The Children’s Hospital & ICH, Multan.

DOI:

https://doi.org/10.29309/TPMJ/2020.27.12.4667

Keywords:

Acute Bronchiolitis, Hypertonic Saline, Length of Hospital Stay, Normal Saline

Abstract

Objectives: To compare mean length of hospital stay (LOHS) after treatment with nebulized hypertonic saline (HS) versus normal saline (NS) in hospitalized children with acute bronchiolitis (AB). Study Design: Randomized Control Trial. Setting: Department of Pediatric Medicine, The Children’s Hospital and Institute of the Child Health, Multan. Period: July 2018 to January 2019. Material & Methods: A total of 206 hospitalized children having AB were enrolled. Group A (n=103) was nebulized with 2 ml of 3 % HS while group B (n=103) was nebulized with 2 ml of 0.9% saline solution. Clinical severity score was calculated daily to monitor progress of patients. Patients were discharged from hospital with clinical severity score of 4 or less and length of hospital stay was noted. Results: Overall, mean age was 5.83±4.48 months. Among 206 patients 139 (67.5%) were males and 67 (32.5%) females. Mean duration of disease was noted to be 3.57+2.2 days. In Group-A, mean LOHS was 36.29+18.4 hours in comparison to 39.15+16.1 hours in Group B (p-value = 0.2365). Conclusion: Nebulized HS 3% and NS 0.9% were not found to have any significant advantage over each other in terms of LOHS among hospitalized children having acute bronchiolitis.

Author Biographies

Maleeha Saleem, The Children’s Hospital & ICH, Multan.

MBBS

Postgraduate Registrar Pediatric Medicine,

Maria Saleem, The Children’s Hospital & ICH, Multan.

MBBS, FCPS (Pediatric Medicine)

Assistant Professor Paediatric Medicine

Asim Khurshid, The Children’s Hospital & ICH, Multan.

MBBS, FCPS (Paediatric Medicine)

Associate Professor Paediatric Medicine

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Published

2020-12-10