Comparison of the effectiveness of Ropivacaine soaked vs bupivacaine soaked dressing for pain relief at split thickness skin graft donor site.

  • Abdul Malik Mujahid Ghazi Medical College Dg Khan.
  • Farrukh Aslam Khalid Jinnah Burn and Reconstructive Surgery Center Lahore.
  • Kashif Mehmood Sheikh Jinnah Burn and Reconstructive Surgery Center Lahore.
  • Muhammad Sheraz Raza Jinnah Burn and Reconstructive Surgery Center, Lahore.
  • Husnain Khan Holy Family Hospital Rawalpindi.
  • Moazzam Nazeer Tarar Jinnah Burn and Reconstructive Surgery Center Lahore.
Keywords: Bupivacaine, Donor Site, Ropivacaine, Soaked Dressing, Split Thickness, Skin Grafting, Verbal Rating Scale

Abstract

Objectives: To compare the mean pain score of ropivacaine soaked dressing versus bupivacaine-soaked dressing for pain relief at the donor site among patients requiring split thickness skin grafting after burns and tissue loss. Study Design: (RCT) Randomized control trial. Setting: Department of Plastic Surgery Jinnah Burn and Reconstructive Surgery Center Lahore. Period: January 1, 2019 to June 31, 2019. Material & Methods: Total 120 patients meeting the inclusion criteria were enrolled and divided randomly into Group-A and Group-B based on lottery method. Group A was dressed with ropivacaine soaked dressing while group-B with bupivacaine-soaked dressing. Patients were asked about pain four hours after the dressing using the verbal rating scale of 0-10. Result: Total 120 patients were included and randomly divided in to two groups. The mean age of ropivacaine group (Group A) patients was 40.82±13.20 years and bupivacaine group (Group-B) patients was 39.70±12.20 years. 56(46.67%) patients were males and 64(53.33%) patients were females.  Male to female ratio was 0.8:1. The mean size of the defect for Group-A patients was 10.43±2.92 and Group B patients was 10.13±2.91. The Mean Visual Rating Scale (VRS) at the baseline for ropivacaine was 7.95 ± 1.04 and for bupivacaine was 8.0167 ±.791 (p =0.695) and VRS (verbal rating scale) at 4 hours of ropivacaine group patients was 1.27±1.13 and in bupivacaine group patients was 2.58±1.61. The statistically significant difference is found between the two study groups for VRS at 4 hours (p-value=0.001). Conclusion: Ropivacaine soaked dressing showed significantly better outcome than bupivacaine-soaked dressing at the donor site among patients requiring split thickness skin grafting after burns and tissue loss.

Author Biographies

Abdul Malik Mujahid, Ghazi Medical College Dg Khan.

MBBS, FCPS

Assistant Professor Plastic Surgery

Farrukh Aslam Khalid, Jinnah Burn and Reconstructive Surgery Center Lahore.

MBBS, FCPS

Assistant Professor Plastic Surgery

Kashif Mehmood Sheikh, Jinnah Burn and Reconstructive Surgery Center Lahore.

MBBS, FCPS

Senior Registrar Plastic Surgery

Muhammad Sheraz Raza, Jinnah Burn and Reconstructive Surgery Center, Lahore.

MBBS, FCPS

Assistant Professor Plastic Surgery

Husnain Khan, Holy Family Hospital Rawalpindi.

MBBS, FCPS

Assistant Professor Plastic Surgery

Moazzam Nazeer Tarar, Jinnah Burn and Reconstructive Surgery Center Lahore.

MBBS, FRCS, FCPS

Professor Plastic Surgery

Published
2020-09-10