Histopathological spectrum of endometrial lesions in cases of abnormal uterine bleeding at a Tertiary Care Hospital.

  • Namra Naeem Faisalabad Medical University, Faisalabad.
  • Afra Samad MMDC, Multan.
  • Safia Sartaj MMDC, Multan.
  • Muhammad Farooq Hitech-IMS. Taxila.
  • Nudrat Fayyaz
  • Muhammad Naeem Choudhary MMDC, Multan.
Keywords: Abnormal Uterine Bleeding, Endometrium, Histopathological Pattern

Abstract

Objectives: To assess histological spectrum of endometrial lesions in abnormal uterine bleeding at a tertiary care hospital. Study Design: Cross Sectional study. Setting: Department of Pathology, Multan Medical & Dental College, Multan and Faisalabad Medical University, Faisalabad. Period: January, 2019 to December, 2019. Material & Methods: Using non – probability purposive sampling technique. Results: A total of 238 ladies presenting with abnormal uterine bleeding were registered in our study. Mean age of these patients with AUB was 47.25 ± 5.57 years (ranging 21 years to 59 years), 158 (66.4%) were aged more than 45 years.  Eighty five (35.7%) were from rural areas while 153 (64.3%) from urban areas. Of these 238 females, 162 (68.1%) were illiterate and 76 (31.9%) were literate. Majority of patients i.e. 218 (91.6%) were married and mean duration of illness was 5.28 ± 3.89 months while 169 (71%) presented within 6 months of illness. Histopathological pattern revealed Proliferative phase endometrium was observed in 69 (29%), endometrial hyperplasia in 59 (24.8%), chronic endometritis in 40 (16.8%), secretory phase in 40 (16.8 %), atrophic endometrium in 30 (12.6%) and endometrial polyps in 10 (4.2%). Conclusion: Histological pattern revealed proliferative endometrium was commonest followed by hyperplasia, secretory phase and chronic endometrium in our study. Disordered proliferative endometrium was commonly observed in married females and those having duration of symptoms more than 6 months. Hyperplasia was more frequent in older patients who were married. Secretory phase was significantly more common in patients with prolonged disease and chronic endometritis was associated with marital status and prolonged disease duration.

Author Biographies

Namra Naeem, Faisalabad Medical University, Faisalabad.

MBBS, FCPS (Histopathology)

Assistant Professor Pathology

Afra Samad, MMDC, Multan.

MBBS, DCP, M.Phil (Morbid Anatomy & Histopathology),

Associate Professor Pathology

 

Safia Sartaj, MMDC, Multan.

MBBS

Demonstrator Pathology

 

Muhammad Farooq, Hitech-IMS. Taxila.

MBBS, FRCS

Assistant Professor Surgery

Muhammad Naeem Choudhary, MMDC, Multan.

MBBS, DCP

Associate Professor Pathology

 

Published
2020-08-10