Accuracy of ultrasound in detection of Hepatocellular Carcinoma in cirrhotic patients.

  • Bushra Riaz DHQ Hospital Faisalabad.
  • Rakhshanda Jabbar DHQ Hospital Faisalabad.
  • Owais Bin Qadeer PMO, PINUM
  • Nasira Parveen Allied Hospital/Faisalabad Medical University, Faisalabad.
  • Fouzia Sultan Allied Hospital, Faisalabad
  • Shakeel Ahmad Allied Hospital/Faisalabad Medical University, Faisalabad.
Keywords: Cirrhotic Patients, Diagnostic Accuracy, Hepatocellular Carcinoma, Ultrasonography

Abstract

Objectives: Evaluate the accuracy of ultrasonography in the diagnosis of hepatocellular carcinoma among cirrhotic patients by comparing it with contrast enhanced multiphasic MRI. Study Design: Cross sectional study. Setting: Radiology Department through OPD\Admitted\emergency, Allied Hospital, Faisalabad. Period: 01-01-2018 to 30-06-2018. Material & Methods: A total of 91 cases, having symptoms of fatigue, weakness, vomiting, nausea, loss of appetite, abdominal pain, weight loss and bloating when the fluid is accumulated in abdominal cavity, itching, spider-like blood vessels on the skin were included in the study. Informed written consent was taken from all the patients or their next of kin after explaining the procedure, objectives and benefits of study. All the patients were examined with Conventional gray scale ultrasound using curvilinear probe of 5MHz and then with 1.5 tesla MR imager. Results: The diagnostic accuracy was computed as 42.86%(n=39) as true positive, 1.10%(n=1) as false positive, 49.45%(n=45) false negative and 6.59%(n=6) had true negative, while 46.43%(sensitivity), 85.71%(specificity), 97.5%(positive predictive value), 88.24%(negative predictive value), and 49.45%(diagnostic accuracy) were calculated. Conclusion: We concluded that the accuracy of ultrasonography for the diagnosis of hepatocellular carcinoma among cirrhotic patients by comparing it with contrast enhanced multiphasic MRI is in agreement with the previous studies, though its accuracy rate is lower but specificity is significantly higher and recommended in our country in low resource settings and tertiary care setups where diagnostic facilities are limited functional.

Author Biographies

Bushra Riaz, DHQ Hospital Faisalabad.

MBBS FCPS (Radiology) 

Consultant Radiologist

 

Rakhshanda Jabbar, DHQ Hospital Faisalabad.

MBBS FCPS Radiology 

Consultant Radiologist

 

Owais Bin Qadeer, PMO, PINUM

MBBS, MS, FCPS, FANMB (Japan).

Consultant Radiologist & Nuclear Physician

 

Nasira Parveen, Allied Hospital/Faisalabad Medical University, Faisalabad.
MBBS, FCPS (Radiology) Consultant Radiogist 
Fouzia Sultan, Allied Hospital, Faisalabad

FCPS

 

Shakeel Ahmad, Allied Hospital/Faisalabad Medical University, Faisalabad.

MBBS

PG Trainee

Department of Radiology and Medical Imaging

 

Published
2020-01-10