Serum calcium level in neonatal seizures presenting at a Tertiary Care Hospital.

  • Nathumal Maheshwari Shaheed Muhtrama Benazir Bhutto Medical College Layari General Hospital Karachi.
  • Nadeem Noor Hamdard College of Medicine and Dentistry Hamdard University Hospital, Karachi.
  • Adnan Bashir Hamdard College of Medicine and Dentistry Hamdard University Hospital, Karachi.
  • Bilawal Hingorjo Dow University of Health Sciences/ Civil Hospital Karachi.
  • Arshad Ali Karachi Institute of Medical Sciences, Malir Cantonment, Karachi.
  • Urooj Tabassum Dow International Medical College, Dow University of Health Sciences,
Keywords: Neonates, Neonatal Seizures, Serum Calcium, Sindh

Abstract

Objectives: The present study was conducted to detect serum calcium level in neonatal seizures presenting at a Tertiary Care Hospital. Study Design: Case control study. Setting: Department of Paediatrics, Shaheed Muhtrama Benazir Bhutto Medical. College Layari General Hospital, Karachi, Sindh. Period: June 2017 to January 2018. Material & Methods: The sample comprised of 100 cases and 100 controls that were selected through non- probability purposive sampling through inclusion and exclusion criteria. Sera were separated through centrifugation of blood for measuring the serum calcium levels. Data was analyzed on SPSS software (SPSS ver 22.0, IBM, Incorporation, USA) at 95% confidence interval (P≤0.05). Results: Of 100 cases and 100 controls, the male and female were noted as 61 vs. 57 and 39 vs. 43 respectively (P > 0.05). In cases, the mean± SD Ca++ was noted as 4.17±1.58 mg/dl while in control it was noted as 8.15± 1.05 mg/dl. Ca++ levels as low as 3.07 mg/dl were noted in the neonatal seizure cases. Normocalcaemia was noted in 81 controls vs. 11 cases and hypocalcaemia in 18 controls vs. 89 cases. Conclusion: The present study reports hypocalcemia is common in neonatal seizures. Pediatricians must evaluate for timely correction of serum calcium to prevent long term neurological sequelies.

Author Biographies

Nathumal Maheshwari, Shaheed Muhtrama Benazir Bhutto Medical College Layari General Hospital Karachi.

MBBS, MCPS, FCPS

Assistant Professor Paediatrics

Nadeem Noor, Hamdard College of Medicine and Dentistry Hamdard University Hospital, Karachi.

MBBS, DCH, FCPS, MRCPCH

Assistant Professor Pediatrics

Adnan Bashir, Hamdard College of Medicine and Dentistry Hamdard University Hospital, Karachi.

MBBS, FCPS

Assistant Professor Paediatrics

Bilawal Hingorjo, Dow University of Health Sciences/ Civil Hospital Karachi.

MBBS, FCPS

Assistant Professor Pediatrics

Arshad Ali, Karachi Institute of Medical Sciences, Malir Cantonment, Karachi.

MBBS, MD

Associate Professor Medicine

Urooj Tabassum, Dow International Medical College, Dow University of Health Sciences,

MBBS, FCPS

Assistant Professor Psychiatry

Published
2021-02-10