A comparison of HDL-c, VLDL-c among diabetics with and without dyslipidemia and healthy controls.

  • Hajira Siddique Foundation University Medical College, Islamabad.
  • Sarah Sadiq Army Medical College, National University of Medical Sciences Abid Majeed Road, Rawalpindi.
  • Asifa Majeed Army Medical College, National University of Medical Sciences Abid Majeed Road, Rawalpindi.
Keywords: Dyslipidemia, HDL-c, Type 2 Diabetes Mellitus, VLDL-c

Abstract

Objectives: To determine and compare the levels of HDL-c and VLDL-c between Diabetic with/without dyslipidemia with normal healthy controls and risk of Cardiovascular disease. Study Design: Cross Sectional Comparative study. Setting: Multidisciplinary Lab I, Department of Biochemistry and Molecular Biology Army Medical College, Rawalpindi. Period: 2 years January 2016 to January 2019. Material & Methods: Total 90 subjects were enrolled in three groups i.e., group I comprised of 30 patients of Diabetic dyslipidemia, group II consisted of 30 patients of Diabetes without dyslipidemia and group III consisted of 30 healthy normal controls. Demographic and clinical data were collected. Data collected was analyzed by SPSS version 22. Results: Male to female ratio included in group I was 1:1.73 and in group II and III was 1:1.5 each. Mean value of the HDL-c among group I was significantly lower as compared to controls. Mean values of the triglycerides (TG) among group I and group II were significantly elevated as compared to the controls. Most of the subjects of group III were doing exercise as part of everyday routine. Conclusion: The HDL-c and TG (VLDL-c) levels are perturbed significantly among Diabetic dyslipidemic patients as compared to Diabetic non-dyslipidemic patients and normal healthy controls. Exercise is an important factor missed by patients to manage their disease.

Author Biographies

Hajira Siddique, Foundation University Medical College, Islamabad.

MBBS, M.Phil

Assistant Professor Biochemistry

Sarah Sadiq, Army Medical College, National University of Medical Sciences Abid Majeed Road, Rawalpindi.

MBBS, M.Phil, PhD.

Associate Professor Biochemistry and Molecular Biology

 

Asifa Majeed, Army Medical College, National University of Medical Sciences Abid Majeed Road, Rawalpindi.

.Phil, PhD., Post Doc

Associate Professor Biochemistry and Molecular Biology

Published
2020-11-10