Severity of thrombocytopenia with different grades of esophageal varices in chronic liver disease patients undergoing gastroscopy’s in a Tertiary Care Hospital.

  • Raj Kumar Lohana JPMC Karachi.
  • Riaz Hussain Awan LUMHS Jamshoro.
  • Seema Nayab LUMHS Jamshoro.
  • Khadim Hussain Awan Sheikh Zayed Hospital Lahore.
  • Faqir Muhammad Awan Shaikh Zaid Hospital Lahore.
Keywords: Esophageal Varices, Non Invasive Predictor of Varices, Portal Hypertension and Thrombocytopenia

Abstract

Objectives: To correlate severity of thrombocytopenia with different grades of esophageal varices in chronic liver disease patients undergoing EGD in a tertiary care hospital. Study Design: Cross sectional study. Setting: Gastroenterology & Hepatology Department at Liaquat National. Period: Six months from Jan to June 2016. Material and Methods: Seventy six subjects of chronic liver disease were recruited and studied for correlation between platelet count and esophageal varices by gastroscopy while the data was analyzed in SPSS version 17. Period: From July 2016 to Dec 2016. Results: There were 55 (72.4%) males and 21 (27.6%) females. The mean age was 45.6 ± 14.7 years. 10 (13.2%) had Hepatitis B, 58 (76.3%) Hepatitis C, 01 (1.3%) Wilson’s disease, 03 (3.9%) Autoimmune disease and 04 (5.3%) Alcoholic liver disease. 09 (11.8%) had Child-Pugh Class A, 41 (53.9%) Class B and 26 (34.2%) had Class C. The mean platelet count was 85/µl ± 40.2/µl. Out of 76 patients 70 (92.1%) had esophageal varices. 23 (30.3%) had grade III varices, 19 (25%) had grade II, 14 (18.4%) each had grade I & IV and 06 (7.9%) had grade 0 varices. Conclusion: thrombocytopenia can predict the occurrence of esophageal varices in cirrhotic population while gastroscopy has high yield for varices.

Author Biographies

Raj Kumar Lohana, JPMC Karachi.

MBBS

Registrar

Department of Gastroenterology Unit-23,

 

Riaz Hussain Awan, LUMHS Jamshoro.

FCPS

Assistant Professor

Department of Gastroenterology

 

Seema Nayab, LUMHS Jamshoro.

FCPS

Assistant Professor

Department of Radiology

 

Khadim Hussain Awan, Sheikh Zayed Hospital Lahore.

MBBS

Resident

Department of Urology

 

Faqir Muhammad Awan, Shaikh Zaid Hospital Lahore.

MBBS                   

Resident

Department of Cardiology

 

Published
2019-10-10