Vitamin B 12 and Folic Acid Deficiency among Malnourished Children with Pancytopenia.

  • Jamal Anwer Sheikh Zayed Medical College, Rahim Yar Khan.
  • Ghulam Mustafa Sheikh Zayed Medical College, Rahim Yar Khan.
  • Sajida Khalid Sheikh Zayed Medical College, Rahim Yar Khan.
  • Shoaib Younis Sheikh Zayed Medical College, Rahim Yar Khan.
  • Riaz ul Haq Sheikh Zayed Medical College, Rahim Yar Khan.
  • Hafiz Muhammad Tayyab RHC Kot Samaba.
Keywords: Folic Acid, Malnourishment, Pancytopenia, Vitamin B 12

Abstract

Objectives: To determine Vitamin B12 and Folic Acid Deficiency among Malnourished Children with Pancytopenia. Study Design: Cross-Sectional study. Setting: Department of Pediatric including both indoor and outdoor, Sheikh Zayed Medical College / Hospital, Rahim Yar Khan. Period: 1st April 2017 to 25th February 2018. Material & Methodology: In this study 60 children having malnutrition and pancytopenia were included. The given performa was filled and record was maintained. Children visiting Paediatric OPD or admitted in the ward having severe malnutrition and pancytopenia in Complete Blood Count were included in the study. While the malnourished Children with normal blood count and children with malignancy e.g; Leukemia, lymphoma etc. were excluded from the study. Results: In this study, mean age of patients was 5 ± 4.2 years, mean weight 10.3± 7.6 kg, mean hemoglobin was 6 ±6.5 g/dl, mean folic acid was 7.7± 6.7 (median 5.6) and mean vitamin B12 563± 537(median 367). Out of total 37 (61.7 %) were male. In this study, grade I malnutrition was 2 (3.3 %), grade II, 17 (28.3%) and grade III, 41(68.3%). Conclusion: Vitamin B 12 & Folic Acid deficiency is found to be a major factor of bone marrow suppression in malnourished children and our result showed that folic acid deficiency was significantly low in females and Vitamin B12 in males.

Author Biographies

Jamal Anwer, Sheikh Zayed Medical College, Rahim Yar Khan.

MBBS, FCPS

Professor Pediatric Medicine,

 

Ghulam Mustafa, Sheikh Zayed Medical College, Rahim Yar Khan.

M.Phil

Associate Professor

Department of Community Medicine

 

Sajida Khalid, Sheikh Zayed Medical College, Rahim Yar Khan.

FCPS

Senior Registrar Pediatric Medicine

 

Shoaib Younis, Sheikh Zayed Medical College, Rahim Yar Khan.

MBBS

PGR Pediatric Medicine

 

Riaz ul Haq, Sheikh Zayed Medical College, Rahim Yar Khan.

FCPS

Senior Registrar Pediatric Medicine

 

Hafiz Muhammad Tayyab, RHC Kot Samaba.

FCPS

Senior Registrar Pediatrician

 

Published
2020-02-10