Comparison of complete blood counts of stable COPD patients at two different altitude in Turkey.

  • Gokhan Perincek Kars Harakani State Hospital, Kars, Turkey
  • Sema Avcı Amasya University Sabuncuoglu Serefeddin Research and Training Hospital, Amasya, Turkey
  • Ilker Yılmam Samsun Chest Diseases and Thoracic Surgery Hospital, Samsun, Turkey
Keywords: Altitude, Chronic Obstructive Pulmonary Disease, Complete Blood Count

Abstract

Introduction: The aim of this study was to evaluate how altitude difference affects complete blood count (CBC) in patients with stable Chronic Obstructive Pulmonary Disease (COPD). Study Design: Cross-sectional study. Setting: Department of Pulmonology, Kars Harakani State Hospital (Group 1) and Samsun Chest Diseases and Thoracic Surgery Hospital (Group 2), Turkey. Period: Six months i.e. from March to September 2018. Material and Methods: A total of 400 patients (200 female, 200 male) with stable COPD were included. For each group, 100 female and 100 male patients were randomly selected from hospitals. Age, BMI (kg/m2), comorbidity, smoking status, CBC were evaluated. Hemoglobin, hematocrit, WBC, MPV, platelet, lymphocyte count and percentage, platelet/lymphocyte rate (PLR), neutrophil count and percentage, neutrophil /lymphocyte rate (NLR), eosinophil count and percentage, PDW, PCT were recorded. Results: Patients living at high altitude were significantly older, had lower weight and had lower FEV1 levels. COPD stages of Group 1 patients were more severe (p<0.001). There were no moderate COPD patients in this group and the patients had fewer comorbidities (43%). Hemoglobin, hematocrit, MPV, WBC, neutrophil count and percentage, NLR and PLR were significantly higher in Group 1 (p<0.001). PDW, PCT, lymphocyte count and percentage, eosinophil count and percentage were significantly higher in Group 2 patients (p<0.001). Conclusion: Hemoglobin, hematocrit, MPV, WBC, neutrophil count and percentage, NLR and PLR were higher in patients living at high altitude. PDW, PCT, lymphocyte count and percentage, eosinophil count and percentage were significantly higher in patients living at low altitude.

Author Biographies

Gokhan Perincek, Kars Harakani State Hospital, Kars, Turkey

MBBS

Consultant

Department of Chest Diseases,

 

Sema Avcı, Amasya University Sabuncuoglu Serefeddin Research and Training Hospital, Amasya, Turkey

MBBS

Assistant Professor

Department of Emergency Medicine,

 

Ilker Yılmam, Samsun Chest Diseases and Thoracic Surgery Hospital, Samsun, Turkey

MBBS

Consultant

Department of Chest Diseases,

 

Published
2019-09-10