COMPARISON OF ONDANSETRON AND METOCLOPRAMIDE IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY UNDER GENERAL ANESTHESIA.

  • Hajra Shuja Ghurki Trust Hospital Lahore.
  • Mehmood Ali Shah Sheikh Zayed Hospital Lahore.
  • Sadaf Bokhari Sheikh Zayed Hospital Lahore.
Keywords: Laparoscopic Cholecystectomy, Metoclopramide, ondansetron, PONV

Abstract

Background: Laparoscopic cholecystectomy is a standard treatment for cholelithiasis. It is a safe and effective treatment in many cases. General anesthesia has a high incidence for PONV. But anti-emetic drugs can help in preventing PONV. Objectives: To compare the efficacy of ondansetron and metoclopramide in patients undergoing laparoscopic cholecystectomy under general anesthesia. Study Design: Randomized controlled trial. Setting: Department of Anaesthesia, Sheikh Zayed Hospital, Lahore. Period: 6 months i.e. from 15-2-2017 to 15-8-2017. Material & Methods: The patients were divided into two groups. Ondansetron was given to group A patients within 15 minutes of induction, and metoclopramide to group B patients within 15 minutes of induction. Then patients were shifted to the ward after surgery and followed-up for 24 hours for assessment of PONV. All the data was entered and analyzed on SPSS version 20. Results: The mean age of patients in group A was 38.40±12.07 years and in group B was 42.63±11.77 years. The efficacy achieved in 53 were from group A and 39 were from group B Statistically significant difference was found between the study groups i.e. p-value=0.003. Conclusion: Ondansetron showed significantly better efficacy than metoclopramide in preventing PONV after laparoscopic cholecystectomy under general anesthesia.

Author Biographies

Hajra Shuja, Ghurki Trust Hospital Lahore.

FCPS

Senior Registrar

Department of Anaesthesia

 

Mehmood Ali Shah, Sheikh Zayed Hospital Lahore.

FCPS

Assistant Professor

Department of Anaesthesia

 

Sadaf Bokhari, Sheikh Zayed Hospital Lahore.

MS Anaesthesia

 

Published
2019-07-10