FREQUENCY AND SEVERITY OF LIVER INVOLVEMENT IN DENGUE VIRUS INFECTION.

  • Masood Tareen Liaquat National Hospital Karachi.
  • Riaz Hussain Awan LUMHS Jamshoro.
  • Seema Nayab LUMHS Jamshoro.
  • Khadim Hussain Awan Sheikh Zayed Hospital Lahore.
Keywords: Bleeding Diathesis, Dengue Virus, Hepatitis, Liver

Abstract

Objectives: To determine the frequency & severity of liver involvement in dengue infection among adults at tertiary care hospital. Period: Six months (9th May 2016 to 9th Nov 2016). Study Design:  Cross-sectional study. Setting: Department of Gastroenterology and Department of Medicine Liaquat National Hospital, Karachi. Patients and Methods: Results: A total of 343 patients with Dengue fever were selected to conduct this study with mean age of 34.67±9.09 years. Mean duration of the fever was 7.31±1.62 days. Mean duration of hospital stay of the patients came out to be 3.50+0.82 days. Severity of liver enzymes derangement was mild in 80 patients (23%), moderate in 246 (72%) & severe in 17(5%). Mortality was seen in 14% (47 patients) & 100% mortality was seen in dengue fever patients with severely deranged Liver enzymes. Conclusion: Dengue fever patients with deranged liver enzymes had statistically worse outcome thus can lead to early recognition of high risk cases.

Author Biographies

Masood Tareen, Liaquat National Hospital Karachi.

MBBS

Resident

Department of Gastroenterology

 

Riaz Hussain Awan, LUMHS Jamshoro.

FCPS

Assistant Professor

Department of Gastroenterology

 

Seema Nayab, LUMHS Jamshoro.

FCPS

Assistant Professor

Department of Radiology

 

Khadim Hussain Awan, Sheikh Zayed Hospital Lahore.

MBBS

Resident

Department of Urology

 

Published
2019-07-10