Frequency of Hyperuricemia in the patients with Acute Myocardial Infarction.

  • Samreen Zafar Memon Liaquat University of Medical & Health Sciences Hyderabad, Sindh, Pakistan.
  • Shahid Hussain Memon Liaquat University of Medical & Health Sciences Hyderabad, Sindh, Pakistan.
  • Shazia Kazi Isra University Hospital Hyderabad.
  • Zain Islam Arain Liaquat University of Medical & Health Sciences Hyderabad, Sindh, Pakistan.
  • Abdul Ghaffar Memon Liaquat University of Medical & Health Sciences Hyderabad, Sindh, Pakistan.
  • Syed Fasih Ahmed Hashmi Liaquat University of Medical & Health Sciences Hyderabad, Sindh, Pakistan.
Keywords: Acute Myocardial Infarction, Hyperuricemia, Pakistan

Abstract

Objectives: This study aims to scientifically fill the gap and provide the scientific data regarding frequency of hyperuricemia in the patients with acute myocardial Infarction admitted at Liaquat University of Medical & Health Sciences, Hyderabad. Study Design: Prospective descriptive case series. Setting: Department of Cardiology, Liaquat University of Medical & Health Sciences, Hyderabad. Period: From 7th Feb 2016 to 6th August 2018. Material and Methods: Was conducted on either gender having age ≥35 to ≤70 years presented with ST elevation myocardial infarction was included in the study. ECG and laboratory investigations were carried out. Relevant investigation like serum uric acid was sent to laboratory. Final outcome was assessed at the end of 5th day, hyperuricemia was labeled if serum uric acid levels above 6.5 mg/dl. All the information was noted in proforma and analyzed using SPSS version 21.0. Results: There were 95 male and 50 female patients. The mean age was 49.57 ± 8.53 years, with range 35 (35 - 70) years. The age of 49 (33.8%) patients was ≤45 years and age of 96 (66.2%) patients was >45 years. 17.9% patients were obese and 50.3% patients were hypertensive. The hyperuricemia was present in 27 (18.6%) patients.  Among patients who were found with hyperuricemia, the mean age was 49.41 ± 8.34 years. The results showed that significant association of hyperuricemia was observed with obesity.  No significant association of hyperuricemia was observed with gender, age, and hypertension. Conclusion: Based on the findings of our study, raised serum uric acid levels are associated with adverse cardiovascular outcome. The prevalence of hyperuricemia is high in a population of patients with acute myocardial infarction.

Author Biographies

Samreen Zafar Memon, Liaquat University of Medical & Health Sciences Hyderabad, Sindh, Pakistan.

MBBS

Post Clinical Fellow

Department of Accident and Emergency

 

Shahid Hussain Memon, Liaquat University of Medical & Health Sciences Hyderabad, Sindh, Pakistan.

MBBS, FCPS

Assistant Professor

Department of Cardiology

 

Shazia Kazi, Isra University Hospital Hyderabad.

MBBS, FCPS (Cardiology)

Assistant Professor

Department of Cardiology

 

Zain Islam Arain, Liaquat University of Medical & Health Sciences Hyderabad, Sindh, Pakistan.

MBBS, Dipcard

Postgraduate Student (MD Cardiology)

Department of Cardiology

 

Abdul Ghaffar Memon, Liaquat University of Medical & Health Sciences Hyderabad, Sindh, Pakistan.

MBBS, FCPS (Cardiology)

Professor and Head

Department of Cardiology

 

Syed Fasih Ahmed Hashmi, Liaquat University of Medical & Health Sciences Hyderabad, Sindh, Pakistan.

MBBS, FCPS (Cardiology)

Professor

Department of Cardiology

 

Published
2020-02-10