AFEBRILE SEIZURES;

FREQUENCY OF HYPOCALCEMIA IN CHILDREN PRESENTING WITH AFEBRILE SEIZURES.

  • Mahwash Rehman Allied Hospital Faisalabad.
  • Fazal Ellahi Bajwa Pediatric Medicine Faisalabad Medical University Faisalabad.
  • Muhammad Aamer Mushtaq Social Security Hospital, Faisalabad.
  • Imran Sarwar Independent Medical College, Faisalabad.
  • Sadida Amir Independent Medical College, Faisalabad.
  • Rashid Nawaz DHQ Hospital, Faisalabad.
Keywords: Children, 2 Months to 2 Years, Afebrile Seizure, Hypocalcemia

Abstract

Background: Seizures are the most common neurologic emergency in pediatrics and can be terrifying for patients and families. They occur in approximately 4-10% of children and account for 1% of all emergency department visits. There are a variety of potential causes for seizures; however, they have a final common pathway which includes abnormal electrical discharges of neurons. The extent of this abnormal discharges and their location in the brain leads to a variety of clinical presentation which range from subtle, non-convulsive events to dramatic generalized convulsions. Most common biochemical abnormality causing seizures is hypocalcemia, which in children may manifest astetany, seizures, muscle cramp, and paresthesia. Objectives: The objective of the study was to: determine the frequency of hypocalcaemia in children presenting with afebrile seizures from age 2 months to 2 years. Study Design: Descriptive cross sectional study. Settings: Pediatric emergency and outpatient department of Pediatric Medicine Unit 1, Independent University Faisalabad. Period: Six months from 01.01.2018 to 30.06.2018. Methodology: After Approval from Ethical committee, 86 children presenting in pediatric emergency of Independent Hospital Faisalabad who meet the inclusion criteria were enrolled in this study. Detailed history and informed consent was obtained from parents of each patient presenting with first episode of afebrile seizure. Blood serum sample was sent to the hospital pathology laboratory for assessment of serum calcium. Routine investigations to rule out other causes of seizures were also done. All the data was recorded on a predesigned performa. Inclusion and exclusion criteria were strictly followed. Results: In this study, out of 86 cases, 55%(n=47) were between 2-12 months of age and 45%(n=39) were between 13-24 months of age, mean+sd was calculated as 12.33+5.27 months, maternal age shows that 72.24%(n=58) were between 18-30years of age and 30.76%(n=29) were between 31-45years of age, mean+sd was calculated as 29.52+3.70 years, 52.38%(n=44) were male and 47.62%(n=42) were females, frequency of hypocalcaemia in children presenting with afebrile seizures from age 2 months to 2 years was recorded in 66.48%(n=56) cases. Conclusion: We concluded that the frequency of hypocalcaemia is higher in children presenting with afebrile seizures from age 2 months to 2 years, and by controlling hypocalcemia, we may reduce the risk of seizures.

Author Biographies

Mahwash Rehman, Allied Hospital Faisalabad.

MBBS

PG Trainee

 

Fazal Ellahi Bajwa, Pediatric Medicine Faisalabad Medical University Faisalabad.

FCPS

Assistant Professor

Department of Pediatric

 

Muhammad Aamer Mushtaq, Social Security Hospital, Faisalabad.

MBBS, MRCP, MHPE Scholar

 

Imran Sarwar, Independent Medical College, Faisalabad.

FCPS

Associate Professor

Department of Pediatric

Sadida Amir, Independent Medical College, Faisalabad.

MBBS, FCPS

Professor

Department of Pediatric

 

Rashid Nawaz, DHQ Hospital, Faisalabad.

MBBS, FCPS

Senior Registrar

 

Published
2019-05-10