BALANCED ANESTHESIA;

COMPARISON OF HEMODYNAMIC CHANGES ON USING PROPOFOL AS TOTAL IV INDUCTION AND BALANCED ANESTHESIA TECHNIQUE (THIOPENTONE, NITROUS OXIDE AND ISOFLURANE).

  • Ijaz Sheikh Allied Hospital, Faisalabad.
  • Samina Aslam Madina Teaching Hospital, Faisalabad.
  • Humaira Ahmad Aziz Fatima Hospital, Faisalabad.
  • Muhammad Rauf Independent University Hospital, Faisalabad.
Keywords: Surgical Procedures, Propofol as Total Intravenous Anaesthesia, Balanced Anaesthesia Technique (Thiopentone-Isoflurane-Nitrous Oxide), Mean Hemodynamic Changes

Abstract

Introduction: Porpofol is currently available popular intravenous anaesthetic agent. It is widely used for induction and maintenance of anaesthesia. Its main advantages are rapid induction and recovery, antiemetic and anticonvulsant effects. It has been used successfully for tracheal intubation without muscle relaxant, day surgery and for insertion of laryngeal mask airway. Its main disadvantages are pain on injection, dose dependent hypotension and severe bradycardia after induction. Objectives: The objective of the study was to compare mean hemodynamic changes using propofol as total intravenous anaesthesia with balanced anaesthesia technique (thiopentone-isoflurane-nitrousoxide). Setting: Department of Anaesthesia, Allied Hospital, Faisalabad. Duration: 6 months after approval of synopsis, from 18-7-2014 to 17-1-2015. Study Design: Randomized control trial. Results: In our study, out of 60 cases(30 in each group), 70%(n=21) in Group-A and 63.33%(n=19) in Group-B were between 12-30 years of age while 30%(n=9) in Group-A and 36.67%(n=11) in Group-B were between 31-60 years of age, mean+sd was calculated as 27.90+8.91 and 29.8+8.49 years respectively. 60%(n=18) in Group-A and 53.33%(n=16) in Group-B were male while 40%(n=12) in Group-A and 46.67%(n=14) in Group-B were females. Comparison of mean hemodynamic changes using propofol as total intravenous anaesthesia with balanced anaesthesia technique (thiopentone-isoflurane-nitrous oxide) shows that heart rate after intubation in Group-A was 83.4+2.36 and 90.36+1.95 in Group-B, p value was 0.001 while mean arterial pressure in Group-A was recorded as 78.6+2.25 and in Group-B 89.43+1.73, p value was 0.000. Conclusion: Propofol as total intravenous anaesthesia shows significanly better stability in haemodynamics when comapred with balanced anaesthesia technique (thiopentone-isoflurane-nitrous oxide) in surgical procedures.

Author Biographies

Ijaz Sheikh, Allied Hospital, Faisalabad.

MBBS, FCPS

Senior Registrar

Department of Anaesthesia and Intensive Care

 

Samina Aslam, Madina Teaching Hospital, Faisalabad.

MBBS, FCPS

Assistant Professor

Department of Anaesthesia and Intensive Care,

Humaira Ahmad, Aziz Fatima Hospital, Faisalabad.

MBBS, FCPS

Assistant Professor

Department of Anaesthesia

 

Muhammad Rauf, Independent University Hospital, Faisalabad.

MBBS, MCPS, DAT

Assistant Professor Chief

Department of Anaesthesiologist,

 

Published
2019-05-10