COAGULASE NEGATIVE STAPHYLOCOCCUS SPECIES

RESISTANCE AND THERAPEUTIC DECISIONS AT THE TURN OF THE NOVEL MILLENNIUM

Authors

  • Eiman Syed The University of Lahore
  • Faiza Nawaz Satti Tehsil Head Quarter Hospital Kotli Sattian
  • Sumaira Mubasher Tehsil Head Quarter Hospital Talagang
  • Farhan Rasheed Allama Iqbal Medical College Lahore, Pakistan
  • Muhammad Ilyas Allama Iqbal Medical College (AIMC&JHL) Lahore, Pakistan
  • Ambereen Imran Anwar Allama Iqbal Medical College, Lahore, Pakistan
  • Waheed uz Zaman

DOI:

https://doi.org/10.29309/TPMJ/2018.25.05.323

Keywords:

CoNS Linezolid, Vancomycin, Teicoplanin, Drug Resistance

Abstract

Objective: Department and sample wise distribution along with drug-resistant
pattern and best therapeutic choice of drugs against Coagulase-negative Staphylococcus
species (CoNS). Study Design: Cross-sectional study. Setting: Department of Microbiology
AIMC Lahore Pakistan. Period: 1st January 2016 to 25th May 2017. Methodology: About
4597 samples were collected from various departments and processed for antimicrobial
resistant testing. Results: Of 4597 samples, culture positive were 40.4% CoNS were 9.0%
and 22.3% of total and total culture positive specimens respectively The highest rate isolation
rate of CONS was found in ICU 32.4%, Sample-wise 34.1% in blood samples.0% resistant
to Linezolid, Teicoplanin, and Vancomycin, while very high resistant rate against penicillin
77.8%, Cotrimoxazole 60%, Methicillin 59.8%,Co-amoxiclav 54%,Clindamycin 48.7%,Fusidic
Acid 463%, Doxycycline 45.1%, Erythromycin 44.9%, Amikacin 42%, Ciprofloxacin 41.8% and
Gentamycin 23%. Conclusion: Linezolid, Vancomycin, and Teicoplanin are the best choice of
drugs while emergence of drug-resistant to other basic drugs is alarming

Author Biographies

Eiman Syed, The University of Lahore

Assistant Professor, UIMLT FAHS

Faiza Nawaz Satti, Tehsil Head Quarter Hospital Kotli Sattian

MBBS
Women Medical Officer

Sumaira Mubasher, Tehsil Head Quarter Hospital Talagang

Women Medical Officer

Farhan Rasheed, Allama Iqbal Medical College Lahore, Pakistan

M.Phil Microbiology
Assistant Professor Pathology,
Microbiology Section, Pathology
Department,

Muhammad Ilyas, Allama Iqbal Medical College (AIMC&JHL) Lahore, Pakistan

Student 4th year Bsc Hons
Pathology Department,

Ambereen Imran Anwar, Allama Iqbal Medical College, Lahore, Pakistan

MBBS, FCPS
Professor of Pathology
Head Dept. of Pathology

Waheed uz Zaman

Assistant Professor
PhD

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Published

2018-05-10