PROSTATIC HYPERPLASIA (BPH);

TAMSULOSIN WITH AND WITHOUT TOLTERODINE IN PATIENTS HAVING BENIGN PROSTATIC HYPERPLASIA (BPH) WITH IRRITATIVE (OVERACTIVE BLADDER) SYMPTOMS.

Authors

  • Khadim Hussain Awan Shaikh Zaid Hospital Lahore.
  • Riaz Hussain Awan LUMHS Jamshoro.
  • Seema Nayab LUMHS Jamshoro.
  • Faqir Muhammad Awan Shaikh Zaid Hospital Lahore.

DOI:

https://doi.org/10.29309/TPMJ/2019.26.02.3096

Keywords:

Tamsulosin, Tolterodine, Benign prostatic hyperplasia (BPH)

Abstract

Objectives: To determine the efficacy of tamsulosin with and without tolterodine in patients having benign prostatic hyperplasia (BPH) with irritative (overactive bladder) symptoms. Study Design: Randomized clinical trial. Setting: Department of Urology and Kidney Transplantation, Sheikh Zayed Hospital Lahore. Period: Six months from July to Dec 2017. Patients and Methods: Sixty patients of BPH had irritative (overactive bladder) & obstructive presentation were recruited. Patients were categorized in two groups and were compared for efficacy according to international prostatic symptom scoring while the data analyzed in SPSS 16. Results: Patients with BPH having irritative (overactive bladder) symptoms, after receiving Tamsulosin with Tolterodine, 76.60% (23/30) of patients reported symptomatic improvement whereas only 40.00 % (12/30) of subjects improved with tamsulosine only. Rate of improvement was observed to be higher in individuals with tamsulosine with tolterodine (Group B) than group A (includes tamsulosin only) with statistical significance) chi-square = 8.297; p=0.004). Conclusion: Efficacy of tamsulosin with tolterodine is higher than tamsulosin alone in subjects with BPH had irritative (overactive bladder) & obstructive symptoms.

Author Biographies

Khadim Hussain Awan, Shaikh Zaid Hospital Lahore.

MBBS

Resident

Department of Urology

 

Riaz Hussain Awan, LUMHS Jamshoro.

FCPS

Assistant Professor

Department of Gastroenterology

 

Seema Nayab, LUMHS Jamshoro.

FCPS

Assistant Professor

Department of Radiology

 

Faqir Muhammad Awan, Shaikh Zaid Hospital Lahore.

MBBS

Resident

Department of Cardiology

 

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Published

2019-02-10