Prevalence of Vitamin D deficiency in patients of Chronic Hepatitis C.

  • Najib Ul Haq LUMHS, Jamshoro.
  • Momina Haq Peshawar Medical College, Riphah International University Islamabad.
  • Farzana Salman Peshawar Medical College, Riphah International University Islamabad.
  • Mohsina Haq Peshawar Medical College, Riphah International University Islamabad.
  • Munaza Khattak Peshawar Medical College, Riphah International University Islamabad.
  • Robina Usman Peshawar Medical College, Riphah International University Islamabad.
  • Arbab Muhammad Kashif Khan
Keywords: Chronic Hepatitis C, Vitamin D, Vitamin D Deficiency

Abstract

Objectives: To determine and compare vitamin D status in chronic hepatitis C patients and normal healthy matching controls. Study Design: A case control study. Setting: A private clinic of Peshawar. Period: 1st November 2015 to 31st January 2016. Material & Methods: Fifty clinically normal young adults and fifty non cirrhotic chronic hepatitis C patients were included in the study. Vitamin D was determined by electro chemiluminescence. Student t test was used to analyze the data in SPSS version 21. Results: The mean age of the study population was 30.68+ 5. Vitamin D deficiency was divided into three categories. 21% of the study population had severe vitamin D deficiency, 33% had mild to moderate deficiency and 46% of the study population had normal levels. Females population were more vitamin D deficient as compared to males (p-value<0.05). Vitamin D levels were comparatively decreased in the non cirrhotic chronic hepatitis C patients. Statistically significant (p value <0.05) results were obtained while comparing means of serum vitamin D of non-cirrhotic chronic hepatitis C patients with healthy matching controls. Conclusion: It is concluded from this study that a significant number of apparently healthy individual have low vitamin D level and some even fall in the severely deficient group without any active complains. Patients with chronic hepatitis C had rather increased levels of vitamin D as compared to normal healthy adults There might be some genetic factors underlying which affects the availability of Vitamin D.

Author Biographies

Najib Ul Haq, LUMHS, Jamshoro.

MBBS, MRCP, FCPS and FRCS

Professor of Medicine

 

Momina Haq, Peshawar Medical College, Riphah International University Islamabad.

MBBS, M-Phil (Physiology)

Assistant Professor Physiology

 

Farzana Salman, Peshawar Medical College, Riphah International University Islamabad.

MBBS, M-Phil (Physiology)

Associate Professor Physiology

 

Mohsina Haq, Peshawar Medical College, Riphah International University Islamabad.

MBBS, M-Phil (Microbiology)

Assistant Professor Microbiology

 

Munaza Khattak, Peshawar Medical College, Riphah International University Islamabad.

MBBS, M-Phil (Physiology)

Assistant Professor Physiology

 

Robina Usman, Peshawar Medical College, Riphah International University Islamabad.

MBBS, M-Phil (Physiology) MHPE,

Associate Professor Physiology

 

Arbab Muhammad Kashif Khan

MBBS

Published
2020-01-10