LIPID ALTERATION

DIABETIC AND OBESE (NON-DIABETIC) PATIENTS

Abstract

Objective: determine serum lipid profile in diabetic and obese non-diabetic patients. Materials: 300 subjects comprising three groups, the first group included 100 diabetic patients (non-obese) with duration of diabetes over 5 years, the second group (obese) included 100 obese subjects (non-diabetic) with duration of obesity over 5 years, and the third group (control) included 100 healthy subjects. Methods: Lipid profile on the serum was performed with an auto analyzer using standard methods. Study design and period: Prospective Analytical Cross Sectional Study conducted in period from September 2006 to January 2008. Results: A significant (p value<0.05) increase in lipid profile results of diabetic and obese patients comparing to control while HDL-C showed significant decreasing. The cholesterol is significantly increased in females than males in diabetic patients, while the triglycerides are significantly decreased in diabetic females. The parameters showed insignificant variations between males and females in obese patients. Conclusions: In comparison to control group, DM & obese groups showed significantly increase in TG, TC, and LDL-C, but significantly decrease in HDL-C. Females showed significant increasing in TC and significant decreasing in DM group, while in obese group females showed insignificant decreasing in TG and TC.