GESTATIONAL DIABETES MELLITUS;

TO COMPARE METFORMIN AND REGULAR INSULIN IN BLOOD SUGAR CONTROL AND NEONATAL OUTCOME IN PATIENTS WITH GESTATIONAL DIABETES MELLITUS

  • Khiaynat Sarwar Hashmi Bahawal Victoria Hospital Bahawalpur.
  • Tasneem Akhtar Bahawal Victoria Hospital Bahawalpur.
  • Sidrah Batool Bahawal Victoria Hospital Bahawalpur.
  • Kokab Saleem Bahawal Victoria Hospital Bahawalpur.
Keywords: Gestational Diabetes, Metformin, Insulin, Macrosomia, Neonatal Hypoglycemia

Abstract

Objectives: To Compare metformin and regular insulin in blood sugar control and neonatal outcome in patients with gestational diabetes mellitus. Material and Method:… Study Design:  Randomized control trial. Place of the Study: Department of Gynecology and Obstetrics, Bahawal Victoria hospital Bahawalpur. Duration of the study.1 year 1st January 2017- 31st December 2017. Sample Size: N=200, one half (group A) receiving Metformin and other half (group B) receiving regular insulin. Results: Blood sugar control depicted by fasting, 2 hr post parandial levels and HbA1c % was similar in both group.coexisting hypertensive complications were seen more in insulin group. Weight gain was also significantly more in insulin group 17 kg on an average as compared to metformin group where average weight gain was 13 kg.Convenience and satisfaction regarding their treatment,more number of patients were satisfied in metformin group. There were significant increase in the mean birth weight of the newborns, need for admission in NICU and Neonatal hypoglycemia in insulin group as compared to metformin group. Conclusion: Metformin when compared to insulin has equal efficacy in controlling maternal blood sugar levels but better neonatal outcome, patient satisfaction and convenience in treatment of gestational Diabetes Mellitus.

Author Biographies

Khiaynat Sarwar Hashmi, Bahawal Victoria Hospital Bahawalpur.

FCPS

Senior Registrar

Department of Gynaecology and Obstetrics

 

Tasneem Akhtar, Bahawal Victoria Hospital Bahawalpur.

MCPS, HFCPS

Associate Professor

Department of Gynaecology and Obstetrics

 

Sidrah Batool, Bahawal Victoria Hospital Bahawalpur.

FCPS

Senior Registrar

Department of Gynaecology and Obstetrics

 

Kokab Saleem, Bahawal Victoria Hospital Bahawalpur.

MBBS

House Officer

Department of Gynaecology and Obstetrics

 

Published
2019-01-10