Introduction:Laboratory is a base of developing teaching and scientific research,also a place of training practical and innovation ability.A robust laboratory experience is a very important part of a high-quality course of instruction in every subject for students interested in research and education. Therefore, a laboratory’s physical design and layout must support and optimize investigation and synthesis of ideas and materials.Objectives:The main objective of biosafety instruction is to guarantee safe practices among specialists in research about labs.Study Design: Review Article. Study Period: June 2017 to December 2017.Setting:Riphah International University, Lahore. Material and Methods: This review article was written to enhance the awareness of biosafety among the students and the professionals. A literature review was done for this study through searching original articles, reviews, case studies and different websites. After analyzing the literature, important aspects of biosafety were highlighted and conclusion was drawn.Results and Conclusion:Regardless of a few instructive workshops by the Pakistan Biological Safety Association (PBSA), consistence with safe practices among researchers stays low. The hazard for research facility authorities working with exceedingly risky operators ought to be limited through preparing and adherence to stringent security conventions and standard working techniques.