ECLAMPTIC PATIENTS;

EFFECTS OF MAGNESIUM SULPHATE AS ANTI CONVULSANT ON MATERNAL CONDITIONS

Authors

  • Farzana Kadri Dow Medical College & Civil Hospital, Karachi
  • Nusrat H. Khan Dow Medical College & Civil Hospital, Karachi
  • Shugufta Shaheen Lady Dufferin Hospital Karachi
  • Muhammad Saeed Liaquat University of Medical & Health Science Jamshoro, Sindh

DOI:

https://doi.org/10.29309/TPMJ/2014.21.03.2037

Keywords:

Eclampsia,, Maternal mortality,, MgSo4

Abstract

Objective: To compare the frequency of fits in the eclamptic patients before and
after use of magnesium sulphate as anticonvulsant and enlist the complications of MgSo4.
Subjects & methods: All the patients with more than 20 weeks, of gestational age, with any parity
were includes in the study. Patients developed fits before giving magnesium sulphate and after
were evaluated, all the patients were monitored for occurrence of complications due to drug.
Magnesium sulphate administered for 24 hours after last fit of delivery and patient’s blood
pressure, pulse, respiratory rate tendon reflexes and urine output was monitored half hourly.
Results: Mostly fits were noted in the patients before the treatment of magnesium sulphate and 1
to 3 fits were noted in the 57.1% of the cases, 28.5% patients were seen with 4 to 6 numbers of the
fits while more than 6 fits were noted in the 14.2% of the cases, and after the treatment (use of
magnesium sulphate) 1 to 3 fits were seen in the 5.7% of the cases, 4 to 6 fits were only in the 2.8%
of the cases while no any patient was noted with above 6 fits. Proteinuria was present in the 80% of
the cases and edema was found in the 42% of the patients Conclusions: In the conclusion of our
study MgSO4 found to be very effective and cheap for control of fits and has lower risk of recurrent
convulsion.

Author Biographies

Farzana Kadri, Dow Medical College & Civil Hospital, Karachi

MBBS MCPS FCPS
Department of gynecology

Nusrat H. Khan, Dow Medical College & Civil Hospital, Karachi

MRCOG, FRCOG
Professor Department of Gynecology

Shugufta Shaheen, Lady Dufferin Hospital Karachi

MCPS, FCPS
Consultant Gynocologist

Muhammad Saeed, Liaquat University of Medical & Health Science Jamshoro, Sindh

MBBS

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Published

2014-06-10