TOXICITY OF ISONIAZID (INH);
ROLE OF BIOCHEMICAL MONITORING TESTS AND HISTORY OF WEAKNESS. THE MANAGEMENT OF PULMONARY TUBERCULOSIS IN PLACEBO CONTROLLED STUDY
DOI:
https://doi.org/10.29309/TPMJ/2012.19.01.1887Keywords:
Tuberculosis,, Anti-tuberculosis therapy,, Placebo,, Isoniazid,, Direct observe Therapy strategy.Abstract
Objective: To compare the untoward effects of isoniazid (inh) and placebo as an anti-tuberculosis therapy in tuberculosis
patients. Study Design: Prospective study. Setting: Free T.B Clinic, Muhammad Medical College Hospital Mirpurkhas Sindh. Period: June
2007 to Dec 2007. Patients, Method and Results: Patients were selected with filling of consent forms from free T.B Clinic. Prospective study of
adverse effects of INH Isoniazid in tuberculosis treatment. Conclusions: It is concluded like other anti-biotics, Isoniazid must be carefully,
mentioned in combination therapy of Anti-Tuberculosis Therapy. The major side effects are those giving rise to serious health hazards, require
discontinuation of the drug and referral to chest physician.
