SUPERDISINTEGRANT ON DISINTEGRANT AND DISSOLUTION

A REVIEW ON INFLUENCE

Authors

  • Muhammad Saquib Qureshi Ziauddin University Karachi, Pakistan.
  • Farya Zafar Ziauddin University Karachi, Pakistan.
  • Huma Ali Ziauddin University Karachi, Pakistan.
  • Kamran Hameed Ziauddin University, Karachi, Pakistan
  • Neelam Mallick Ziauddin University Karachi, Pakistan.
  • Sohail Khan Ziauddin University Karachi, Pakistan.
  • Saba Ajaz Baloch Ziauddin University Karachi, Pakistan.

DOI:

https://doi.org/10.29309/TPMJ/2016.23.10.1716

Abstract

In tablet formulation superdisintegrants are added to accelerate the rate of tablet
deaggregation and thus enhancing the rate of tablet dissolution. In this review article we gather
the information related to the superdisintegrants, their mechanism of actions and their impact
on disintegration and dissolution processes. The easiest way to achieve quick release is to use
a superdisintegrants with appropriate concentrations of excipients. Different superdisintegrants
are usually added to facilitate the tablet disintegration, thus increasing the rate of tablet
dissolution.

Author Biographies

Muhammad Saquib Qureshi, Ziauddin University Karachi, Pakistan.

Faculty of Pharmacy,

Farya Zafar, Ziauddin University Karachi, Pakistan.

Faculty of Pharmacy,

Huma Ali, Ziauddin University Karachi, Pakistan.

Faculty of Pharmacy,

Kamran Hameed, Ziauddin University, Karachi, Pakistan

Faculty of Medicine,
Ziauddin Medical College,

Neelam Mallick, Ziauddin University Karachi, Pakistan.

Faculty of Pharmacy,

Sohail Khan, Ziauddin University Karachi, Pakistan.

Faculty of Pharmacy,

Saba Ajaz Baloch, Ziauddin University Karachi, Pakistan.

Faculty of Pharmacy,

Downloads

Published

2016-10-10

Issue

Vol. 23 No. 10 (2016): Vol. 23 No. 10

Section

Articles