CARCINOMA OF LARYNX

THE DIAGNOSTIC ACCURACY OF COMPUTED TOMOGRAPHY SCAN IN EVALUATION OF THYROID CARTILAGE INVASION

Abstract

Objectives: The objective of this study was to determine the diagnostic
accuracy of CT scan in detecting thyroid cartilage invasion by carcinoma of larynx keeping
histopathological findings as a gold standard. Study Design: Cross sectional and descriptive
study. Setting: Department of Radiology of LUMHS, And Karachi Institute of Radiotherapy &
Nuclear Medicine. Period: February 2013 to August 2015. Subjects and Methods: Overall 86
patients were incorporated in this study. All these patients subsequently had their histopathology.
The CT outcomes were then contrasted with histopathological results & measures of variables
calculated, were based on the results. Results: Fifty patients were men & 36 patients were
women. The ages varied from 31 to 65yrs with mean age of 50yrs. The specificity & sensitivity
of CT in diagnosing thyroid cartilage invasion was 84.5% and 93.3% respectively. Accurateness
of CT in diagnosing thyroid cartilage invasion was 86.05%. Conclusion: The study established
the specificity, sensitivity, negative as well as positive predictive value and accuracy of CT
scan for the detection of thyroid cartilage invasion as 84.5%, 93.3%, 98.4%, 56% and 86.05%
respectively. Very low negative predictive value was found in patients of age more than 50 years.