COMPARISON OF KETAMINE NEBULISATION WITH KETAMINE GARGLES IN ATTENUATING POSTOPERATIVE SORE THROAT.
Objectives: To compare the effect of ketamine nebulization and ketamine gargle
on post operative sore throat. Study Design: Randomized control trial. Setting: Department of
Anaesthesia Ibn e Sina Hospital. Multan and National, Lahore. Period: May 2016 to May 2017.
Methodology: After provision form ethical committee and informed consent to be included in
study. Patients of age 20-60 years, ASA status I and II, elective surgeries under GA and both sex
were included in the study through consecutive sampling technique. SPSS software was used to
analyze all variables included in the study continuous variables were measured and presented
as mean and standard deviation, categorical measurement were measured in numbers and
percents. Chi square test was applied to check the difference among both groups. P value ≤
0.05 was considered as significant. Results: Overall, 100% (n=160) patients were included, in
this study; divided into two equal groups, 50% (n=80) in each, gargled ketamine group (GK
group) and nebulization group (NK group) respectively. The incidence of postoperative sore
throat at 0, 2, 4, and 24 hours, in GK group, was (n=8) 40%, (n=4) 20%, (n=3) 15% and (n=3)
15%respectively. While, at corresponding time point in group NK it was (n=1) 5%, (n=7) 35%,
(n=4) 20% and (n=2) 10%respectively. Conclusion: The observations of our study revealed
that ketamine nebulization and ketamine gargles having no significant difference in reduction
of POST incidence.