BETA THALASSEMIA

IMPAIRED GLUCOSE TOLERANCE IN CHILDREN WITH BLOOD TRANSFUSION DEPENDENT BETA THALASSEMIA

  • Iqbal Ahmed Shahida Islam Medical College, Lodhran.
  • Muhammad Ammar Sadiq District Headquarter Hospital (DHQ), Lodhran.
  • Umair Arshad District Headquarter Hospital, Lodhran.
  • Hafiz Muhammad Anwar ul Haq District Headquar Hospital, Lodhran.
  • Sobia Tabassum Civil Hospital, Bahawalpur.
  • Arshia Sabir Sahiwal Medical College, Sahiwal.
  • Muhammad Ejaz ul Haq Mayo Hospital, Lahore.
Keywords: Thalassemia Major, Blood Transfusion, Impaired Glucose Tolerance

Abstract

Background: Inadequate Blood Transfusion is responsible for various problems
in children with Thalasseima. On the other hand, repeated transfusions are related with hazards.
About 25-50% of the children with thalassemia major have impaired glucose tolerance (IGT)
or diabetes. Objectives: To find out the frequency of IGT in children with blood transfusion
dependent β thalassemia. Study Design: Descriptive analytical study. Setting: Department of
Pediatrics, Shahida Islam Teaching Hospital, Lodhran. Period: 1st July 2017 to 31st December
2017. Material and Methods: Known 120 cases of beta Thalassemia major children between
3-17 years of age that were regularly transfused. Demographics, disease history and personal
information regarding all the patients were collected. Glucose tolerance test was performed
and Serum ferritin levels were measured. Results were analyzed by SPSS software version
20.0. Results: There were 78 (65.0%) children between 3-10 years and 42 (35.0%) between
11-17 years. There were 70(58.3) male and 50 (41.7%) female. Frequency of impaired glucose
tolerance was noted in 15 (12.5%). Conclusion: Frequency of IGT is high amongst children with
thalassemia major having regular blood transfusions.

Author Biographies

Iqbal Ahmed, Shahida Islam Medical College, Lodhran.

MBBS, FCPS
Assistant Professor and Head
Department of Pediatrics

Muhammad Ammar Sadiq, District Headquarter Hospital (DHQ), Lodhran.

MBBS
Medical Officer

Umair Arshad, District Headquarter Hospital, Lodhran.

MBBS
Medical Officer

Hafiz Muhammad Anwar ul Haq, District Headquar Hospital, Lodhran.

MBBS, MCPS, FCPS
Consultant
Department Pediatrition.

Sobia Tabassum, Civil Hospital, Bahawalpur.

MBBS, FCPS
Senior Registrar

Arshia Sabir, Sahiwal Medical College, Sahiwal.

MBBS
Demonstrator

Muhammad Ejaz ul Haq, Mayo Hospital, Lahore.

MBBS
PGR

Published
2018-09-10