C – REACTIVE PROTEIN

IN PATIENTS WITH ACUTE APPENDICITIS

Abstract

Acute appendicitis is the most common abdominal surgical emergency despite
advances in radiographic imaging and diagnostic laboratory investigations; the diagnosis of
acute appendicitis remains challenge. Objectives: To evaluate the C-reactive protein in patients
with acute appendicitis. Patients and methods: This cross sectional descriptive study of six
months study was conducted at Liaquat University Hospital Hyderabad. All the patients with
acute appendicitis were admitted in the ward and were further evaluated for C-reactive protein.
The data was analyzed in SPSS 16 and the frequency and percentage was calculated. Results:
One hundred subjects with acute appendicitis were recruited and studies. The mean age ±SD of
the patients was 27.83±07.52 in overall population while it was 29.73±06.64 and 25.84±04.92
in male and female subjects with acute appendicitis. The CRP was raised in 60% patients. The
distribution of age in relation to gender and CRP was statisitically significant (p= 0.01 and
<0.01) whereas the CRP was also observed as statistically significant in context to gender
and histopathology (p= 0.02 and 0.03) respectively. The mean ±SD of CRP was 7.53±1.52
in overall population while it was 6.84±1.64 and 8.65±1.53 in male and female patients with
raised CRP. Conclusions: The CRP was elevated in patients with acute appendicitis.