GJB2 GENE

ITS CONTRIBUTION TO GENETIC DEAFNESS? : A REVIEW

Authors

  • Sana Ullah Quaid-i-Azam University Islamabad Islamic Republic of Pakistan
  • Khaista Rahman Quaid-i-Azam University Islamabad Islamic Republic of Pakistan
  • Muhammad Tariq Quaid-i-Azam University Islamabad Islamic Republic of Pakistan
  • Tauseef Ahmad Hazara University Mansehra Khyber Pakhtunkhwa Islamic Republic of Pakistan

DOI:

https://doi.org/10.29309/TPMJ/2015.22.02.1362

Keywords:

Genetic Deafness, GJB2 gene, Mutations

Abstract

This article reviews the most prevalent sensory illness of mammals especially
humans – Genetic Deafness or hearing loss (HL). For genetic hearing loss more than 100
candidate genes have been discovered. The most common candidate gene of these all that is
found all around the world is GJB2 gene. Different types of mutations are found in GJB2 gene.
Some of these mutations are non-sense while some are sense mutations. This study is focus on
mutation in GJB2 gene and its prevalence in different region of the world.

Author Biographies

Sana Ullah, Quaid-i-Azam University Islamabad Islamic Republic of Pakistan

Department of Animal Sciences

Khaista Rahman, Quaid-i-Azam University Islamabad Islamic Republic of Pakistan

Department of Biotechnology

Muhammad Tariq, Quaid-i-Azam University Islamabad Islamic Republic of Pakistan

Department of Biotechnology

Tauseef Ahmad, Hazara University Mansehra Khyber Pakhtunkhwa Islamic Republic of Pakistan

Department of Microbiology

Downloads

Published

2015-02-10

Issue

Vol. 22 No. 02 (2015): Vol: 22 No. 02

Section

Articles