SENILE CATARACT
SERUM LIPIDS A MODIFIABLE RISK FACTOR
DOI:
https://doi.org/10.29309/TPMJ/2015.22.04.1336Keywords:
Cataract, Serum Triglycerides, Serum LDL, Serum cholesterol, Serum HDL, Risk factors for cataractAbstract
Objective: To estimate the serum lipid profile of patients having different types
of senile cataract and compare them with that of the controls. Study Design: Observational
case control study. Place of study: Tertiary care centre in the city of Lahore, Pakistan. Period:
Six months. Methods: We selected fifty patients with senile cataract and fifty control individuals
from tertiary care hospital of Lahore. History, ophthalmic and systemic examinations were
done. Fasting serum samples were taken for estimation of lipid profile from all the subjects.
Results: In the patient group, female to male ratio was 1.63:1. 78% patients had Nuclear
cataract, 16% had cortical and 6% had posterior sub capsular type of senile cataract. Serum
Triglycerides, Cholesterol, LDL, HDL and VLDL of patients were compared with controls. The
p-value of cholesterol, LDL and HDL was non-significant. The p-value of triglycerides and VLDL
was significant. Conclusions: Serum Triglycerides and VLDL are modifiable risk factors in the
development of senile cataract in Pakistani patients. Serum Triglycerides is the only lipid, which
has shown consistent results related to cataract development in different parts of the world.
Other lipids show variable results in different countries.
